Researchers Map Pathways to Protective Antibodies for an HIV Vaccine
The findings advance progress toward HIV vaccine design
DURHAM, N.C. – A Duke Health-led research team has described both the pathway of HIV protective antibody development and a synthetic HIV outer envelope mimic that has the potential to induce the antibodies with vaccination.
“A goal for an HIV-1 vaccine is to induce broadly neutralizing antibodies,” said senior author Barton F. Haynes, M.D., director of the Duke Human Vaccine Institute (DHVI). “One strategy for the induction of these desirable antibodies is to find a way to develop a small portion of the envelope’s structure that these desired antibodies recognize – something we have now shown is possible.”
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