Publications Durham NC | HIV Publications & Articles

Envelope-specific antibodies and antibody-derived molecules for treating and curing HIV infection.

Ferrari G, Haynes BF, Koenig S, Nordstrom JL, Margolis DM, Tomaras GD. Nat Rev Drug Discov. 2016 Dec;15(12):823-834. doi: 10.1038/nrd.2016.173. Epub 2016 Oct 7.

HIV-1 Envelope Mimicry of Host Enzyme Kynureninase Does Not Disrupt Tryptophan Metabolism

Bradley T, Yang G, Ilkayeva O, Holl TM, Zhang R, Zhang J, Santra S, Fox CB, Reed SG, Parks R, Bowman CM, Bouton-Verville H, Sutherland LL, Scearce RM, Vandergrift N, Kepler TB, Moody MA, Liao HX, Alam SM, McLendon R, Everitt JI, Newgard CB, Verkoczy L, Kelsoe G, Haynes BF. J Immunol. 2016 Dec 15;197(12):4663-4673. Epub 2016 Nov 14.

Amino Acid Changes in the HIV-1 gp41 Membrane Proximal Region Control Virus Neutralization Sensitivity

Bradley T, Trama A, Tumba N, Gray E, Lu X, Madani N, Jahanbakhsh F, Eaton A, Xia SM, Parks R, Lloyd KE, Sutherland LL, Scearce RM, Bowman CM, Barnett S, Abdool-Karim SS, Boyd SD, Melillo B, Smith AB 3rd, Sodroski J, Kepler TB, Alam SM, Gao F, Bonsignori M, Liao HX, Moody MA, Montefiori D, Santra S, Morris L, Haynes BF. EBioMedicine. 2016 Aug 31. pii: S2352-3964(16)30402-9. doi: 10.1016/j.ebiom.2016.08.045. [Epub ahead of print]

Induction of HIV Neutralizing Antibody Lineages in Mice with Diverse Precursor Repertoires

Tian M, Cheng C, Chen X, Duan H, Cheng HL, Dao M, Sheng Z, Kimble M, Wang L, Lin S, Schmidt SD, Du Z, Joyce MG, Chen Y, DeKosky BJ, Chen Y, Normandin E, Cantor E, Chen RE, Doria-Rose NA, Zhang Y, Shi W, Kong WP, Choe M, Henry AR, Laboune F, Georgiev IS, Huang PY, Jain S, McGuire AT, Georgeson E, Menis S, Douek DC, Schief WR, Stamatatos L, Kwong PD, Shapiro L, Haynes BF, Mascola JR, Alt FW. Cell. 2016 Sep 8;166(6):1471-1484.e18. doi: 10.1016/j.cell.2016.07.029.

Amino Acid Changes in the HIV-1 gp41 Membrane Proximal Region Control Virus Neutralization Sensitivity.

Immune perturbations in HIV-1-infected individuals who make broadly reactive neutralizing antibodies

This is the author's version of the work. It is posted here by permission of the AAAS for personal use, not for redistribution. The definitive version was published in Science Immunology {Vol 1, July 29, 2016}, {DOI: 10.1126/sciimmunol.aag0851}

Novel Monoclonal Antibodies for Studies of Human and Rhesus Macaque Secretory Component and Human J-Chain

Zhang R, Alam SM, Yu JS, Scearce R, Lockwood B, Hwang KK, Parks R, Permar S, Brandtzaeg P, Haynes BF, Liao HX. Monoclon Antib Immunodiagn Immunother. 2016 Jul 7. [Epub ahead of print]

Envelope-specific B-cell populations in African green monkeys chronically infected with simian immunodeficiency virus

Zhang R, Martinez DR, Nguyen QN, Pollara J, Arifin T, Stolarchuk C, Foulger A, Amos JD, Parks R, Himes JE, Wang M, Edwards RW, Trama AM, Vandergrift N, Colvin L, Dewar K, Juretic N, Wasserscheid J, Ferrari G, Liao HX, Permar SR. Nat Commun. 2016 Jul 6;7:12131. doi: 10.1038/ncomms12131.

Developmental Pathway of the MPER-Directed HIV-1-Neutralizing Antibody 10E8

Soto C, Ofek G, Joyce MG, Zhang B, McKee K, Longo NS, Yang Y, Huang J, Parks R, Eudailey J, Lloyd KE, Alam SM, Haynes BF; NISC Comparative Sequencing Program, Mullikin JC, Connors M, Mascola JR, Shapiro L, Kwong PD. PLoS One. 2016 Jun 14;11(6):e0157409. doi: 10.1371/journal.pone.0157409. eCollection 2016.

Envelope residue 375 substitutions in simian-human immunodeficiency viruses enhance CD4 binding and replication in rhesus macaques

Li H, Wang S, Kong R, Ding W, Lee FH, Parker Z, Kim E, Learn GH, Hahn P, Policicchio B, Brocca-Cofano E, Deleage C, Hao X, Chuang GY, Gorman J, Gardner M, Lewis MG, Hatziioannou T, Santra S, Apetrei C, Pandrea I, Alam SM, Liao HX, Shen X, Tomaras GD, Farzan M, Chertova E, Keele BF, Estes JD, Lifson JD, Doms RW, Montefiori DC, Haynes BF, Sodroski JG, Kwong PD, Hahn BH, Shaw GM. Proc Natl Acad Sci U S A. 2016 Jun 14;113(24):E3413-22. doi: 10.1073/pnas.1606636113. Epub 2016 May 31.

Publications