Publications Durham NC | HIV Publications & Articles

Potent and broad HIV-neutralizing antibodies in memory B cells and plasma

LaTonya D. Williams, Gilad Ofek, Sebastian Schätzle, Jonathan R. McDaniel, Xiaozhi Lu, Nathan I. Nicely, Liming Wu, Caleb S. Lougheed, Todd Bradley, Mark K. Louder, Krisha McKee, Robert T. Bailer, Sijy O’Dell, Ivelin S. Georgiev, Michael S. Seaman, Robert J. Parks, Dawn J. Marshall, Kara Anasti, Guang Yang, Xiaoyan Nie, Nancy L. Tumba, Kevin Wiehe, Kshitij Wagh, Bette Korber, Thomas B. Kepler, S. Munir Alam, Lynn Morris, Gift Kamanga, Myron S. Cohen, Mattia Bonsignori, Shi-Mao Xia, David C. Montefiori, Garnett Kelsoe, Feng Gao, John R. Mascola, M. Anthony Moody, Kevin O. Saunders, Hua-Xin Liao, Georgia D. Tomaras, George Georgiou and Barton F. Haynes. Science Immunology 27 Jan 2017: Vol. 2, Issue 7, DOI: 10.1126/sciimmunol.aal2200

Influence of the Envelope Gp120 Phe 43 Cavity on HIV-1 Sensitivity to ADCC Responses.

Prévost J, Zoubchenok D, Richard J, Veillette M, Pacheco B, Coutu M, Brassard N, Parsons MS, Ruxrungtham K, Bunupuradah T, Tovanabutra S, Hwang KK, Moody MA, Haynes BF, Bonsignori M, Sodroski J, Kaufmann DE, Shaw GM, Chenine AL, Finzi A.

Resistance to type 1 interferons is a major determinant of HIV-1 transmission fitness

Iyer SS, Bibollet-Ruche F, Sherrill-Mix S, Learn GH, Plenderleith L, Smith AG, Barbian HJ, Russell RM, Gondim MV, Bahari CY, Shaw CM, Li Y, Decker T, Haynes BF, Shaw GM, Sharp PM, Borrow P, Hahn BH. Proc Natl Acad Sci U S A. 2017 Jan 9. pii: 201620144. doi: 10.1073/pnas.1620144114. [Epub ahead of print]

Polyvalent vaccine approaches to combat HIV-1 diversity.

Korber B, Hraber P, Wagh K, Hahn BH.

Broadly Neutralizing Antibodies Display Potential for Prevention of HIV-1 Infection of Mucosal Tissue Superior to That of Nonneutralizing Antibodies

Cheeseman HM, Olejniczak NJ, Rogers PM, Evans AB, King DF, Ziprin P, Liao HX, Haynes BF, Shattock RJ.J Virol. 2016 Dec 16;91(1). pii: e01762-16. Print 2017 Jan 1. PMID: 27795431

Genetic and structural analyses of affinity maturation in the humoral response to HIV-1.

Kepler TB, Wiehe K.

Host controls of HIV broadly neutralizing antibody development.

Kelsoe G, Haynes BF.

Immunodominance of Antibody Recognition of the HIV Envelope V2 Region in Ig-Humanized Mice

Wiehe K, Nicely NI, Lockwood B, Kuraoka M, Anasti K, Arora S, Bowman CM, Stolarchuk C, Parks R, Lloyd KE, Xia SM, Duffy R, Shen X, Kyratsous CA, Macdonald LE, Murphy AJ, Scearce RM, Moody MA, Alam SM, Verkoczy L, Tomaras GD, Kelsoe G, Haynes BF. J Immunol. 2016 Dec 23. pii: 1601640. doi: 10.4049/jimmunol.1601640. [Epub ahead of print]

Small-Molecule CD4 Mimetics Sensitize HIV-1-Infected Cells to Antibody-Dependent Cellular Cytotoxicity by Antibodies Elicited by Multiple Envelope Glycoprotein Immunogens in Nonhuman Primates

Ding S, Verly MM, Princiotto A, Melillo B, Moody AM, Bradley T, Easterhoff D, Roger M, Hahn BH, Madani N, Smith AB 3rd, Haynes BF, Sodroski J, Finzi A. AIDS Res Hum Retroviruses. 2016 Dec 19. doi: 10.1089/AID.2016.0246. [Epub ahead of print]

Tissue memory B cell repertoire analysis after ALVAC/AIDSVAX B/E gp120 immunization of rhesus macaques.

Luo K, Liao HX, Zhang R, Easterhoff D, Wiehe K, Gurley TC, Armand LC, Allen AA, Von Holle TA, Marshall DJ, Whitesides JF, Pritchett J, Foulger A, Hernandez G, Parks R, Lloyd KE, Stolarchuk C, Sawant S, Peel J, Yates NL, Dunford E, Arora S, Wang A, Bowman CM, Sutherland LL, Scearce RM, Xia SM, Bonsignori M, Pollara J, Edwards RW, Santra S, Letvin NL, Tartaglia J, Francis D, Sinangil F, Lee C, Kaewkungwal J, Nitayaphan S, Pitisuttithum P, Rerks-Ngarm S, Michael NL, Kim JH, Alam SM, Vandergrift NA, Ferrari G, Montefiori DC, Tomaras GD, Haynes BF, Moody MA. JCI Insight. 2016 Dec 8;1(20):e88522.

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