Publications Durham NC | HIV Publications & Articles

The β20-β21 of gp120 is a regulatory switch for HIV-1 Env conformational transitions

A. Herschhorn, C. Gu, F. Moraca, X. Ma, M. Farrell, A. B. Smith, 3rd, M. Pancera, P. D. Kwong, A. Schon, E. Freire, C. Abrams, S. C. Blanchard, W. Mothes, J. G. Sodroski, Nat Commun 8, 1049 (2017); published online EpubOct 19 (10.1038/s41467-017-01119-w).

A strongly selected mutation in the HIV-1 genome is independent of T cell responses and neutralizing antibodies

D. Liu, C. Wang, B. Hora, T. Zuo, N. Goonetilleke, M. K. P. Liu, M. Berrong, G. Ferrari, A. J. McMichael, T. Bhattacharya, A. S. Perelson, F. Gao, Retrovirology 14, 46 (2017); published online EpubOct 10 (10.1186/s12977-017-0371-4).

Adaptation of HIV-1 to cells with low expression of the CCR5 coreceptor

N. Espy, B. Pacheco, J. Sodroski, Virology 508, 90-107 (2017); published online EpubAug (10.1016/j.virol.2017.04.033).

CD8+ T cell programming by cytomegalovirus vectors: applications in prophylactic and therapeutic vaccination

K. Fruh, L. Picker, Curr Opin Immunol 47, 52-56 (2017); published online EpubAug (10.1016/j.coi.2017.06.010).

Induction of a Tier-1-Like Phenotype in Diverse Tier-2 Isolates by Agents That Guide HIV-1 Env to Perturbation-Sensitive

J. Johnson, Y. Zhai, H. Salimi, N. Espy, N. Eichelberger, O. DeLeon, Y. O'Malley, J. Courter, A. B. Smith, 3rd, N. Madani, J. Sodroski, H. Haim, Nonnative States. J Virol 91, (2017); published online EpubAug 1 (10.1128/jvi.00174-17).

Sequence intrinsic somatic mutation mechanisms contribute to affinity maturation of VRC01-class HIV-1 broadly neutralizing antibodies

J. K. Hwang, C. Wang, Z. Du, R. M. Meyers, T. B. Kepler, D. Neuberg, P. D. Kwong, J. R. Mascola, M. G. Joyce, M. Bonsignori, B. F. Haynes, L. S. Yeap, F. W. Alt, Proc Natl Acad Sci U S A 114, 8614-8619 (2017); published online EpubAug 8 (10.1073/pnas.1709203114).

Impaired Downregulation of NKG2D Ligands by Nef Proteins from Elite Controllers Sensitizes HIV-1-Infected Cells to Antibody-Dependent Cellular Cytotoxicity

N. Alsahafi, J. Richard, J. Prevost, M. Coutu, N. Brassard, M. S. Parsons, D. E. Kaufmann, M. Brockman, A. Finzi, J Virol 91, (2017); published online EpubAug 15 (10.1128/jvi.00109-17).

Immune perturbations in HIV-1-infected individuals who make broadly neutralizing antibodies

M. A. Moody, I. Pedroza-Pacheco, N. A. Vandergrift, C. Chui, K. E. Lloyd, R. Parks, K. A. Soderberg, A. T. Ogbe, M. S. Cohen, H. X. Liao, F. Gao, A. J. McMichael, D. C. Montefiori, L. Verkoczy, G. Kelsoe, J. Huang, P. R. Shea, M. Connors, P. Borrow, B. F. Haynes, Immune perturbations in HIV-1-infected individuals who make broadly neutralizing antibodies. Sci Immunol 1, aag0851 (2016); published online EpubJul 29 (10.1126/sciimmunol.aag0851).

What Are the Primary Limitations in B-Cell Affinity Maturation, and How Much Affinity Maturation Can We Drive with Vaccination? Breaking through Immunity's Glass Ceiling.

G. Kelsoe, B. F. Haynes, Cold Spring Harb Perspect Biol, (2017); published online EpubJun 19 (10.1101/cshperspect.a029397).

Pentavalent HIV-1 vaccine protects against simian-human immunodeficiency virus challenge

T. Bradley, J. Pollara, S. Santra, N. Vandergrift, S. Pittala, C. Bailey-Kellogg, X. Shen, R. Parks, D. Goodman, A. Eaton, H. Balachandran, L. V. Mach, K. O. Saunders, J. A. Weiner, R. Scearce, L. L. Sutherland, S. Phogat, J. Tartaglia, S. G. Reed, S. L. Hu, J. F. Theis, A. Pinter, D. C. Montefiori, T. B. Kepler, K. K. Peachman, M. Rao, N. L. Michael, T. J. Suscovich, G. Alter, M. E. Ackerman, M. A. Moody, H. X. Liao, G. Tomaras, G. Ferrari, B. T. Korber, B. F. Haynes, Nat Commun 8, 15711 (2017); published online EpubJun 8 (10.1038/ncomms15711).

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