CHAVI Reagents

See the list below for information regarding CHAVI Cell Lines, Immunogens, Human Monoclonal Antibodies, Mouse Monoclonal Antibodies, Nonhuman Primate Monoclonal Antibodies, Neutralizing Antibodies Resources and Viral Sequences: 

Cell Lines 

Please contact Sabrina Arora or Robert Parks.

  1. 293T-JRFL
    Unique ID: HV13631
  2. 293T-JRFL APAmut 140CF
    Unique ID: HV13627

  3. 293T-63521 TC21 140C
    Unique ID: HV13214

  4. 293T-624008 TA5 140C
    Unique ID: HV13215

  5. 293T-6235714 D3 140C
    Unique ID: HV13216

  6. 293T-902114 B2 140C
    Unique ID: HV13217

  7. 293T-089C 140C
    Unique ID: HV13245

  8. 293T-1086C 140C
    Unique ID: HV13246

  9. 293T-700010040 C9 140C
    Unique ID: HV13255

Immunogens 

Please contact Caroline Cockrell or Robert Parks.

  1. rVV92RWO20
    Unique ID: HV10101
    Category: Recombinant vaccinia virus

  2. rVVJRFL 140CF
    Unique ID: HV10201
    Category: Recombinant vaccinia virus

  3. rVV6101 120
    Unique ID: HV10202
    Category: Recombinant vaccinia virus

  4. rVV97ZA012 140CFI
    Unique ID: HV10301
    Category: Recombinant vaccinia virus 

  5. rVVA.00MSA-4076 140CF
    Unique ID: HV00064
    Category: Recombinant vaccinia virus

  6. rVVC.Du123 140CF
    Unique ID: HV00065
    Category: Recombinant vaccinia virus

  7. rVVG.DRCBL 140CF
    Unique ID: HV00066
    Category: Recombinant vaccinia virus 

  8. rVVAE.97CNGX2F 140CF
    Unique ID: HV00067
    Category: Recombinant vaccinia virus

Human Monoclonal Antibodies 

1.7B
Category: CD4i MAbs
Contact person: James Robinson
Contact E-mail: jrobinso@tulane.edu

4.8D
Category: CD4i MAbs
Contact person: James Robinson
Contact E-mail: jrobinso@tulane.edu

5.8H
Category: CD4i MAbs
Contact person: James Robinson
Contact E-mail: jrobinso@tulane.edu

2.5E
Category: CD4i MAbs
Contact person: James Robinson
Contact E-mail: jrobinso@tulane.edu

4.12D
Category: CD4i MAbs
Contact person: James Robinson
Contact E-mail: jrobinso@tulane.edu

4.8E(IgG3)
Category: CD4i MAbs
Contact person: James Robinson
Contact E-mail: jrobinso@tulane.edu

ED11
Category: CD4i MAbs
Contact person: James Robinson
Contact E-mail: jrobinso@tulane.edu

ED47
Category: CD4i MAbs
Contact person: James Robinson
Contact E-mail: jrobinso@tulane.edu

1.1A
Category: CD4i MAbs
Contact person: James Robinson
Contact E-mail: jrobinso@tulane.edu

1.12A
Category: CD4i MAbs
Contact person: James Robinson
Contact E-mail: jrobinso@tulane.edu

1.12D
Category: CD4i MAbs
Contact person: James Robinson
Contact E-mail: jrobinso@tulane.edu

3.1H
Category: CD4i MAbs
Contact person: James Robinson
Contact E-mail: jrobinso@tulane.edu

2.1C
Category: CD4i MAbs
Contact person: James Robinson
Contact E-mail: jrobinso@tulane.edu

4.7E
Category: CD4i MAbs
Contact person: James Robinson
Contact E-mail: jrobinso@tulane.edu

2.1C
Category: CD4i MAbs
Contact person: James Robinson
Contact E-mail: jrobinso@tulane.edu

E51
Category: CD4i MAbs
Contact person: James Robinson
Contact E-mail: jrobinso@tulane.edu

1.9E
Category: CD4i MAbs
Contact person: James Robinson
Contact E-mail: jrobinso@tulane.edu

ED10
Category: CD4i MAbs
Contact person: James Robinson
Contact E-mail: jrobinso@tulane.edu

ED49
Category: CD4i MAbs
Contact person: James Robinson
Contact E-mail: jrobinso@tulane.edu

LF17
Category: CD4i MAbs
Contact person: James Robinson
Contact E-mail: jrobinso@tulane.edu

1.5E
Category: CD4 BS
Contact person: James Robinson
Contact E-mail: jrobinso@tulane.edu

F91
Category: CD4 BS
Contact person: James Robinson
Contact E-mail: jrobinso@tulane.edu

4E
Category: CD4 BS
Contact person: James Robinson
Contact E-mail: jrobinso@tulane.edu

19B
Category: V3 MAbs
Contact person: James Robinson
Contact E-mail: jrobinso@tulane.edu

CO11
Category: V3 MAbs
Contact person: James Robinson
Contact E-mail: jrobinso@tulane.edu

2.1E
Category: V3 MAbs
Contact person: James Robinson
Contact E-mail: jrobinso@tulane.edu

3.9F
Category: V3 MAbs
Contact person: James Robinson
Contact E-mail: jrobinso@tulane.edu

F2A3
Category: V3 MAbs
Contact person: James Robinson
Contact E-mail: jrobinso@tulane.edu

1.4E
Category: V3 MAbs
Contact person: James Robinson
Contact E-mail: jrobinso@tulane.edu

5.8C
Category: V3 MAbs
Contact person: James Robinson
Contact E-mail: jrobinso@tulane.edu

1.4C
Category: A32 and A32-like
Contact person: James Robinson
Contact E-mail: jrobinso@tulane.edu

1.4G
Category: A32 and A32-like
Contact person: James Robinson
Contact E-mail: jrobinso@tulane.edu

5.8A
Category: A32 and A32-like
Contact person: James Robinson
Contact E-mail: jrobinso@tulane.edu

A32
Category: A32 and A32-like
Contact person: James Robinson
Contact E-mail: jrobinso@tulane.edu

4.6H
Category: A32 and A32-like
Contact person: James Robinson
Contact E-mail: jrobinso@tulane.edu

22C
Category: A32 and A32-like
Contact person: James Robinson
Contact E-mail: jrobinso@tulane.edu

EH21
aa31-50  89.6 peptide
Category: C1-C5 MAbs
Contact person: James Robinson
Contact E-mail: jrobinso@tulane.edu

C11
Category: C1-C5 MAbs
Contact person: James Robinson
Contact E-mail: jrobinso@tulane.edu

2.12A
Category: C1-C5 MAbs
Contact person: James Robinson
Contact E-mail: jrobinso@tulane.edu

2.3B
Category: C1-C5 MAbs
Contact person: James Robinson
Contact E-mail: jrobinso@tulane.edu

8.2A
Category: C1-C5 MAbs
Contact person: James Robinson
Contact E-mail: jrobinso@tulane.edu

2.3A
C terminal peptide
Category: C1-C5 MAbs
Contact person: James Robinson
Contact E-mail: jrobinso@tulane.edu

7B2
Category: gp41 MAbs
Contact person: James Robinson
Contact E-mail: jrobinso@tulane.edu

KU19
Category: gp41 MAbs
Contact person: James Robinson
Contact E-mail: jrobinso@tulane.edu

KU31
Category: gp41 MAbs
Contact person: James Robinson
Contact E-mail: jrobinso@tulane.edu

2.2B
Category: gp41 MAbs
Contact person: James Robinson
Contact E-mail: jrobinso@tulane.edu

LG1.1C
AC13
Category: Autologous Neutralizing human Mabs
Contact person: James Robinson
Contact E-mail: jrobinso@tulane.edu

5.9C
AC10
Category: Autologous Neutralizing human Mabs
Contact person: James Robinson
Contact E-mail: jrobinso@tulane.edu

6.4C
ZM205
Category: Autologous Neutralizing human Mabs
Contact person: James Robinson
Contact E-mail: jrobinso@tulane.edu

13.6A
ZM205
Category: Autologous Neutralizing human Mabs
Contact person: James Robinson
Contact E-mail: jrobinso@tulane.edu

9.7G
ZM205
Category: Autologous Neutralizing human Mabs
Contact person: James Robinson
Contact E-mail: jrobinso@tulane.edu

8.9D
ZM205
Category: Autologous Neutralizing human Mabs
Contact person: James Robinson
Contact E-mail: jrobinso@tulane.edu

6.1C
ZM205
Category: Autologous Neutralizing human Mabs
Contact person: James Robinson
Contact E-mail: jrobinso@tulane.edu

10.9D
ZM205
Category: Autologous Neutralizing human Mabs
Contact person: James Robinson
Contact E-mail: jrobinso@tulane.edu

1.6A
ZM205
Category: Autologous Neutralizing human Mabs
Contact person: James Robinson
Contact E-mail: jrobinso@tulane.edu

7.8A
ZM205
Category: Autologous Neutralizing human Mabs
Contact person: James Robinson
Contact E-mail: jrobinso@tulane.edu

7.2C
CHAVI 703010054
Category: Autologous Neutralizing human Mabs
Contact person: James Robinson
Contact E-mail: jrobinso@tulane.edu

10.1C
A32-like
Category: HMAbs from CHAVI 040
Contact person: James Robinson
Contact E-mail: jrobinso@tulane.edu

12.6D
gp41 (no competitiion with 7B2 or 22B)
Category: HMAbs from CHAVI 040
Contact person: James Robinson
Contact E-mail: jrobinso@tulane.edu

16.11A
gp41 (no competitiion with 7B2 or 22B)
Category: HMAbs from CHAVI 040
Contact person: James Robinson
Contact E-mail: jrobinso@tulane.edu

15.5A
gp41 (no competitiion with 7B2 or 22B)
Category: HMAbs from CHAVI 040
Contact person: James Robinson
Contact E-mail: jrobinso@tulane.edu

3.4F
CD4i broad reactivity
Category: HMAbs from CHAVI 040
Contact person: James Robinson
Contact E-mail: jrobinso@tulane.edu

2.9C
CD4i inducible cross reactivity
Category: HMAbs from CHAVI 040
Contact person: James Robinson
Contact E-mail: jrobinso@tulane.edu

9.6D
CD4i 040 strain specific
Category: HMAbs from CHAVI 040
Contact person: James Robinson
Contact E-mail: jrobinso@tulane.edu

14.2A
ZM221
Category: Uncharacterized Mabs Non-neutralizing
Contact person: James Robinson
Contact E-mail: jrobinso@tulane.edu

6.10B
ZM221
Category: Uncharacterized Mabs Non-neutralizing
Contact person: James Robinson
Contact E-mail: jrobinso@tulane.edu

9.5E
ZM221
Category: Uncharacterized Mabs Non-neutralizing
Contact person: James Robinson
Contact E-mail: jrobinso@tulane.edu

2.6C
N terminus; non-neutralizing
Category: HMAbs HIV-2
Contact person: James Robinson
Contact E-mail: jrobinso@tulane.edu

1.7A
V4 dependent
Category: HMAbs HIV-2
Contact person: James Robinson
Contact E-mail: jrobinso@tulane.edu

1.10C
V4 dependent
Category: HMAbs HIV-2
Contact person: James Robinson
Contact E-mail: jrobinso@tulane.edu

B23
V4 dependent
Category: HMAbs HIV-2
Contact person: James Robinson
Contact E-mail: jrobinso@tulane.edu

7.4H
V4 dependent
Category: HMAbs HIV-2
Contact person: James Robinson
Contact E-mail: jrobinso@tulane.edu

6.10F
V3
Category: HMAbs HIV-2
Contact person: James Robinson
Contact E-mail: jrobinso@tulane.edu

6.10B
CD4 BS
Category: HMAbs HIV-2
Contact person: James Robinson
Contact E-mail: jrobinso@tulane.edu

1.4H
CD4i
Category: HMAbs HIV-2
Contact person: James Robinson
Contact E-mail: jrobinso@tulane.edu

1.4B
overlaps V3
Category: HMAbs HIV-2
Contact person: James Robinson
Contact E-mail: jrobinso@tulane.edu

Mouse Monoclonal Antibodies 

Please contact Caroline Cockrell or Rob Parks.

  1. 703
    Specificity: CD44 RBC Protein Regulated by In(Lu) Gene

  2. 704
    Specificity: CD44 RBC Protein Regulated by In(Lu) Gene

  3. 948
    Specificity: CD44

  4. 710
    Specificity: CD7 p41, 3A1 Antigen, T Cell specific

  5. 727
    Specificity: CD7, 3A1, p41 T Cell Antigen

  6. 728
    Specificity: CD7, 3A1, p41 T Cell Antigen

  7. 926
    Specificity: CD7, T Cell Specific-gp40

  8. 927
    Specificity: CD7, T Cell Specific-gp40

  9. 1393
    Specificity: CD6

  10. 1396
    Specificity: CD6

  11. 1397
    Specificity: CD6

  12. 1398
    Specificity: CD6

  13. 706
    Specificity: CD7

  14. 711
    Specificity: 3A1 CD7

  15. TBD
    Specificity: HIV-1 gp41 envelope

  16. TBD
    Specificity: HIV-1 gp41 envelope

  17. TBD
    Specificity: HIV-1 V3 loop of gp120

  18. TBD
    Specificity: HIV-1 multiple subtypes, envelope glycoproteins

Nonhuman Primate Monoclonal Antibodies 

  1. 2.1E
    Category: Rhesus V3 Mabs
    Contact person: James Robinson
    Contact E-mail: jrobinso@tulane.edu
     
  2. E23
    Category: Rhesus V3 Mabs
    Contact person: James Robinson
    Contact E-mail: jrobinso@tulane.edu
     
  3. 4.2B
    Category: Rhesus V3 Mabs
    Contact person: James Robinson
    Contact E-mail: jrobinso@tulane.edu
     
  4. MB25
    Category: Rhesus V3 Mabs
    Contact person: James Robinson
    Contact E-mail: jrobinso@tulane.edu
     
  5. 2.10A
    Category: Rhesus V3 Mabs
    Contact person: James Robinson
    Contact E-mail: jrobinso@tulane.edu
     
  6. 22G
    SF162
    Category: Autologous Neutralizing Rhesus Mabs
    Contact person: James Robinson
    Contact E-mail: jrobinso@tulane.edu
     
  7. 25B
    SF162
    Category: Autologous Neutralizing Rhesus Mabs
    Contact person: James Robinson
    Contact E-mail: jrobinso@tulane.edu
     
  8. 23E
    SF162
    Category: Autologous Neutralizing Rhesus Mabs
    Contact person: James Robinson
    Contact E-mail: jrobinso@tulane.edu
     
  9. LW26
    SF162
    Category: Autologous Neutralizing Rhesus Mabs
    Contact person: James Robinson
    Contact E-mail: jrobinso@tulane.edu
     
  10. 1.8E
    SF162
    Category: Autologous Neutralizing Rhesus Mabs
    Contact person: James Robinson
    Contact E-mail: jrobinso@tulane.edu
     
  11. 3.10E
    SF162
    Category: Autologous Neutralizing Rhesus Mabs
    Contact person: James Robinson
    Contact E-mail: jrobinso@tulane.edu
     
  12. LV23
    SF162
    Category: Autologous Neutralizing Rhesus Mabs
    Contact person: James Robinson
    Contact E-mail: jrobinso@tulane.edu
     
  13. LV24
    SF162
    Category: Autologous Neutralizing Rhesus Mabs
    Contact person: James Robinson
    Contact E-mail: jrobinso@tulane.edu
     
  14. 1.7F
    SF162
    Category: Autologous Neutralizing Rhesus Mabs
    Contact person: James Robinson
    Contact E-mail: jrobinso@tulane.edu
     
  15. 1.6F
    SF162 - V3
    Category: Autologous Neutralizing Rhesus Mabs
    Contact person: James Robinson
    Contact E-mail: jrobinso@tulane.edu
     
  16. 3.9A
    SF162
    Autologous Neutralizing Rhesus Mabs
    Contact person: James Robinson
    Contact E-mail: jrobinso@tulane.edu
     
  17. 2.8F
    SF162
    Category: Autologous Neutralizing Rhesus Mabs
    Contact person: James Robinson
    Contact E-mail: jrobinso@tulane.edu
     
  18. 1.10D
    SF162
    Category: Autologous Neutralizing Rhesus Mabs
    Contact person: James Robinson
    Contact E-mail: jrobinso@tulane.edu
     
  19. 3.5F
    89.6
    Category: Autologous Neutralizing Rhesus Mabs
    Contact person: James Robinson
    Contact E-mail: jrobinso@tulane.edu
     
  20. 3.10H
    89.6
    Category: Autologous Neutralizing Rhesus Mabs
    Contact person: James Robinson
    Contact E-mail: jrobinso@tulane.edu

Neutralizing Antibodies Resource

The "Standardized Assessments of Neutralizing Antibodies for HIV/AIDS Vaccine Development" resource is a collaborative site between the Comprehensive Antibody Vaccine Immune Monitoring Consortium (CA-VIMC) under Dr. David Montefiori at Duke University and the Los Alamos National Laboratory (LANL).  The site provides detailed information for making standardized assessments of neutralizing antibodies against HIV, SIV and SHIV using molecularly cloned Env-pseudotyped viruses in an optimized and validated luciferase (Luc) reporter gene assay.

Standardized Assessments of Neutralizing Antibodies for HIV/AIDS Vaccine Development

Viral Sequences 

CHAVI viral sequences are available in the Los Alamos National Laboratory (LANL) Database.

  1. To search for CHAVI viral sequences, please visit the HIV Sequence Database search interface:http://www.hiv.lanl.gov/components/sequence/HIV/search/search.html.

  2. Open the "Patient Information" tab.

  3. In the "Project" field, select CHAVI from the menu.

  4. Enter any other search criteria desired (viral subtype, genomic region, etc.) and search.

CHAVI acute viral sequences are available in the Special Interest Alignments section of the Database.