The Duke Center for HIV/AIDS Vaccine Immunology and Immunogen Discovery (CHAVI-ID) was funded by the National Institute of Allergy and Infectious Diseases to overcome the major immunological roadblocks in HIV vaccine design and development. More

Press Releases

A T cell and the Human Immunodeficiency Virus

Unique individual demonstrates desired immune response to HIV virus
March 10, 2014
Duke News and Communications

As luck would have it: one of the proteins in milk protects infants against HIV infection
The Economist
October 26, 2013

New artificial protein mimics a part of the HIV outer coat
Duke News and Communications
October 21, 2013

Recent Publications

Reversion and T Cell Escape Mutations Compensate the Fitness Loss of a CD8+ T Cell Escape Mutant in Their Cognate Transmitted/Founder Virus.
Song H, Hora B, Bhattacharya T, Goonetilleke N, Liu MK, Wiehe K, Li H, Iyer SS, McMichael AJ, Perelson AS, Gao F. PLoS One. 2014 Jul 16;9(7):e102734. doi: 10.1371/journal.pone.0102734. eCollection 2014.

Affinity maturation in an HIV broadly neutralizing B-cell lineage through reorientation of variable domains.
Fera D, Schmidt AG, Haynes BF, Gao F, Liao HX, Kepler TB, Harrison SC. Proc Natl Acad Sci U S A. 2014 Jun 30. pii: 201409954. [Epub ahead of print]

Proteome-wide analysis of HIV-specific naive and memory CD4+ T cells in unexposed blood donors.
Campion SL, Brodie TM, Fischer W, Korber BT, Rossetti A, Goonetilleke N, McMichael AJ, Sallusto F. J Exp Med. 2014 Jun 30;211(7):1273-80. doi: 10.1084/jem.20130555. Epub 2014 Jun 23.

Video Presentations

Broadly neutralizing HIV-1 antibody identified in a lupus patient
March 11, 2014
Dr. Barton Haynes, Duke CHAVI-ID Director, discusses recent findings from a study led by Duke CHAVI-ID investigators in which a broadly neutralizing antibody was identified in a lupus patient who was chronically infected with HIV.