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The Duke Center for HIV/AIDS Vaccine Immunology and Immunogen Discovery (CHAVI-ID) was funded by the National Institute of Allergy and Infectious Diseases to overcome the major immunological roadblocks in HIV vaccine design and development. More

Press Releases

A T cell and the Human Immunodeficiency Virus

New Research from Boston and Duke Universities Offers New Hope for HIV Vaccine Development
Boston University School of Medicine
August 13, 2014

Gut Flora Influences HIV Immune Response
Duke News and Communications
August 13, 2014

Powerful HIV Antibodies May Require Assist from Second Antibody to Develop
National Institute of Allergy and Infectious Diseases
July 25, 2014

Recent Publications

HIV-1 Envelope gp41 Antibodies Can Originate from Terminal Ileum B Cells that Share Cross-Reactivity with Commensal Bacteria.
Trama AM, Moody MA, Alam SM, Jaeger FH, Lockwood B, Parks R, Lloyd KE, Stolarchuk C, Scearce R, Foulger A, Marshall DJ, Whitesides JF, Jeffries TL Jr, Wiehe K, Morris L, Lambson B, Soderberg K, Hwang KK, Tomaras GD, Vandergrift N, Jackson KJ, Roskin KM, Boyd SD, Kepler TB, Liao HX,Haynes BF. Cell Host Microbe. 2014 Aug 13;16(2):215-226. doi: 10.1016/j.chom.2014.07.003.

Progress in HIV-1 vaccine development.
Haynes BF, Moody MA, Alam M, Bonsignori M, Verkoczy L, Ferrari G, Gao F, Tomaras GD, Liao HX, Kelsoe G. J Allergy Clin Immunol. 2014 Jul;134(1):3-10. doi: 10.1016/j.jaci.2014.04.025. Epub 2014 Jun 26. Review.

Recombinant Bacillus Calmette-Guérin vectors prime for strong cellular responses to SIV Gag in rhesus macaques.
Sixsmith JD, Panas MW, Lee S, Gillard GO, White K, Lifton MA, Balachandran H, Mach L, Miller JP, Lavine C, DeMarco CT, Tomaras GD, Gee C, Porcelli SA, Larsen MH, Frothingham R, Schmitz JE, Jacobs WR Jr, Haynes BF, Letvin NL, Korioth-Schmitz B. Clin Vaccine Immunol. 2014 Jul 30. pii: CVI.00324-14. [Epub ahead of print]

Video Presentations


Broadly neutralizing HIV-1 antibody identified in a lupus patient
March 11, 2014
Dr. Barton Haynes, Duke CHAVI-ID Director, discusses recent findings from a study led by Duke CHAVI-ID investigators in which a broadly neutralizing antibody was identified in a lupus patient who was chronically infected with HIV.